TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC3 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [18F]-FDHT from androgen receptor in human LNCAP/AR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC2 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductase; value ranges from 36-60 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair