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Found 324 with Last Name = 'baker' and Initial = 'wr'
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006122(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.360nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280221((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.370nMpH: 6.0Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280229((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.380nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006125(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.470nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280237((1S,2R,3S)-2-(2-Methoxymethoxy-ethanesulfonyl)-3-p...)
Affinity DataIC50:  0.480nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280235((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.590nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50011231(2-Benzyl-N-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo...)
Affinity DataIC50:  0.600nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280224((1S,2R,3S)-2-Methanesulfonyl-3-phenyl-cyclopropane...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280222((1S,2R,3S)-2-Ethenesulfonyl-3-phenyl-cyclopropanec...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280227((1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phen...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006138(2-(Morpholine-4-carbonyl)-3-phenyl-cyclopropanecar...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280219(3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-...)
Affinity DataIC50:  0.770nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280231((1S,2R,3R)-2-Cyclohexyl-3-(propane-2-sulfonyl)-cyc...)
Affinity DataIC50:  0.790nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50046796((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...)
Affinity DataIC50:  0.870nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006147(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:In vitro potency against purified renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006157(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006189((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50011228((R)-2-Benzyl-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-...)
Affinity DataIC50:  0.990nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006206(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006185(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006152(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006152(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280226((1R,2S,3R)-2-(2-Methoxymethoxy-ethanesulfonyl)-3-p...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006161(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.10nMpH: 6.0Assay Description:In vitro potency against purified renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006123(2,3-Diphenyl-cyclopropanecarboxylic acid [1-(1-cyc...)
Affinity DataIC50:  1.10nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50036999((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  1.10nMpH: 7.4Assay Description:Tested in vitro for its ability to inhibit the human plasma renin at pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006161(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.10nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50011229(2-Benzyl-N-[1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo...)
Affinity DataIC50:  1.10nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280236((1S,2R,3S)-2-Benzenesulfonyl-3-phenyl-cyclopropane...)
Affinity DataIC50:  1.20nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006148(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.20nMpH: 6.0Assay Description:In vitro potency against purified renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50011228((R)-2-Benzyl-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Compound was evaluated for the inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006211(CHEMBL49218 | {4-[2-(2-tert-Butoxycarbonylamino-3-...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50036995(1N-[3-methylamino(cyano imino)methylaminopropyl]-5...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Tested in vitro for its ability to inhibit the human plasma renin at pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006176(CHEMBL264194 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50036979(1N-[3-cyanoimino(methylsulfanyl)methylaminopropyl]...)
Affinity DataIC50:  1.30nMAssay Description:Tested in vitro for its ability to inhibit the human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006208(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006150(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006204(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006141(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006195((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006197(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280234((S)-2-Benzyl-N-[(S)-1-((1S,2R,3S)-1-cyclohexylmeth...)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50280230((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50036977(1N-[3-amino(cyanoimino)methylaminopropyl]-5-[1-[1-...)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:Tested in vitro for its ability to inhibit the human plasma renin at pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006184((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006196((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006148(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50011227(2-Benzyl-N-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo...)
Affinity DataIC50:  1.5nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50036989((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:Tested in vitro for its ability to inhibit the human plasma renin at pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50006207(CHEMBL301395 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.70nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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