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Found 363 with Last Name = 'christophe' and Initial = 'b'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176723((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176735((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176732((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176718(1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-p...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176723((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176712(1-cyclopentyl-3-(3-methoxyquinuclidin-3-yl)-1-phen...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176708((R)-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenyl-1-(...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176706(1-(6-fluoropyridin-3-yl)-3-(3-methoxyquinuclidin-3...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.339nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176729(3-(3-methoxyquinuclidin-3-yl)-1-phenyl-1-(pyridin-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176735((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  0.407nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176717(1-(3-methoxyquinuclidin-3-yl)-3-phenylhept-1-yn-3-...)
Affinity DataKi:  0.630nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176711((R)-1,1-bis(3-fluorophenyl)-3-(3-methoxyquinuclidi...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176726(1-(2-fluoropyridin-3-yl)-3-(3-methoxyquinuclidin-3...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176708((R)-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenyl-1-(...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176732((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403947(CHEMBL85996)
Affinity DataKi:  0.794nMAssay Description:In vitro affinity for muscarinic M3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22548(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4,6-trimeth...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/mole EC50:  2nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000240(CHEMBL435796)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176722((R)-1,1-bis(4-fluorophenyl)-3-(3-methoxyquinuclidi...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421552(CHEMBL108200)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403940(CHEMBL85892)
Affinity DataKi:  1nMAssay Description:In vitro affinity for muscarinic M3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176704(3-(3-methoxyquinuclidin-3-yl)-1-phenyl-1-(pyrimidi...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176714(1-cyclobutyl-3-(3-methoxyquinuclidin-3-yl)-1-pheny...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176729(3-(3-methoxyquinuclidin-3-yl)-1-phenyl-1-(pyridin-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176716(3-(3-methoxyquinuclidin-3-yl)-1-phenyl-1-(pyridin-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50209328(1-(2-cyclopropyl-5-methyl-6-(pyrrolidin-1-yl)pyrim...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]N-methylscopolamine from human recombinant M3 muscarinic receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403944(CHEMBL84993)
Affinity DataKi:  1.30nMAssay Description:In vitro affinity for muscarinic M3 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50165019(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000252(CHEMBL136347)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000241(CHEMBL138824)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421561(CHEMBL419742)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403945(CHEMBL314831)
Affinity DataKi:  1.60nMAssay Description:Antagonism of Muscarinic M3 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig urinary bladderMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421567(CHEMBL109937)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421562(CHEMBL108889)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000238(CHEMBL336305)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000236(CHEMBL140080)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176704(3-(3-methoxyquinuclidin-3-yl)-1-phenyl-1-(pyrimidi...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000248(CHEMBL139750)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000239(CHEMBL342266)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22538(4-Benzyl-1H-imidazole derivative, 19 | 4-{[3-(2-ph...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403943(CHEMBL82512)
Affinity DataKi:  2nMAssay Description:Antagonism of Muscarinic M3 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig urinary bladderMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403942(CHEMBL310132)
Affinity DataKi:  2nMAssay Description:Antagonism of Muscarinic M3 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig urinary bladderMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50176718(1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-p...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000255(CHEMBL139088)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000221(CHEMBL336251)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50403946(CHEMBL83982)
Affinity DataKi:  2.5nMAssay Description:Antagonism of Muscarinic M3 receptors as displacement of concentration response curve of carbachol on isolated guinea-pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000243(CHEMBL423913)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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