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Found 399 with Last Name = 'nara' and Initial = 'f'
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238110(CHEMBL4088766)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238110(CHEMBL4088766)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238108(CHEMBL4070230)
Affinity DataIC50:  2nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238103(CHEMBL4070323)
Affinity DataIC50:  2nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  2nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  2nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50:  3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  4nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  4nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238106(CHEMBL4072943)
Affinity DataIC50:  5nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238114(CHEMBL4093575)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238103(CHEMBL4070323)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238120(CHEMBL4097020)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238123(CHEMBL4061565)
Affinity DataIC50:  8nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238117(CHEMBL4092081)
Affinity DataIC50:  8nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238108(CHEMBL4070230)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238114(CHEMBL4093575)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238106(CHEMBL4072943)
Affinity DataIC50:  13nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238107(CHEMBL4064367)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238116(CHEMBL4079006)
Affinity DataIC50:  15nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50395775(CHEMBL2164857)
Affinity DataIC50:  15nMAssay Description:Partial agonist activity at mouse GPR142 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50:  16nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238117(CHEMBL4092081)
Affinity DataIC50:  19nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238114(CHEMBL4093575)
Affinity DataIC50:  21nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50:  30nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208895(CHEMBL397081 | sodium 4-[(4-butoxyphenyl)thio]-20-...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238116(CHEMBL4079006)
Affinity DataIC50:  42nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238104(CHEMBL4072871)
Affinity DataIC50:  48nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238101(CHEMBL4104118)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208889(sodium 4-[(4-butoxyphenyl)thio]-20-(1,12-dihydroxy...)
Affinity DataIC50:  80nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238122(CHEMBL4083387)
Affinity DataIC50:  83nMAssay Description:Inhibitory activity against rat adenylate kinase II was determined in the presence of ATP, non competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50:  93nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208901(CHEMBL239876 | sodium 4-[(4-butoxyphenyl)thio]-20-...)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50: >100nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238103(CHEMBL4070323)
Affinity DataIC50:  102nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238113(CHEMBL4067686)
Affinity DataIC50:  109nMAssay Description:Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238123(CHEMBL4061565)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238104(CHEMBL4072871)
Affinity DataIC50:  124nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208900(CHEMBL396365 | sodium 4-[(4-butoxyphenyl)thio]-20-...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238119(CHEMBL4075207)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against rat adenylate kinase II was determined in the presence of AMP, competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238104(CHEMBL4072871)
Affinity DataIC50:  170nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238101(CHEMBL4104118)
Affinity DataIC50:  181nMAssay Description:Inhibition of human CYP11B1 expressed in HEK293A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208887(CHEMBL239659 | sodium 4-[(4-butoxyphenyl)thio]-20-...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50208884(CHEMBL241104 | sodium 20-(1-hydroxytridec-2-yn-1-y...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cell membrane by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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