BDBM50238105 CHEMBL4099824

SMILES CS(=O)(=O)N1CCC(CC1)C(O)c1cncnc1Nc1ccc(F)cc1

InChI Key InChIKey=IAYSRSZRQAAKQV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238105   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  300nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  300nMAssay Description:Inhibition of rat CYP11B2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed