Compile Data Set for Download or QSAR
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Found 47 with Last Name = 'patterson' and Initial = 'se'
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19263(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 33...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19257(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 27...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19261(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 31...)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19263(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 33...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19255(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 25...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50192467(CHEMBL384114 | P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19256(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 26...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19257(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 27...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50192467(CHEMBL384114 | P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...)
Affinity DataKi:  37nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19258(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 28...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19259(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 29...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19261(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 31...)
Affinity DataKi:  49nM ΔG°:  -41.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50192469(CHEMBL215311 | P1-(adenosin-5'-yl)methylenephospho...)
Affinity DataKi:  60nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19266(CHEMBL410745 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  66nM ΔG°:  -41.0kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19260(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 30...)
Affinity DataKi:  73nM ΔG°:  -40.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19255(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 25...)
Affinity DataKi:  84nM ΔG°:  -40.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50192469(CHEMBL215311 | P1-(adenosin-5'-yl)methylenephospho...)
Affinity DataKi:  87nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19262(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 32...)
Affinity DataKi:  94nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19262(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 32...)
Affinity DataKi:  96nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19266(CHEMBL410745 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  108nM ΔG°:  -39.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19253(CHEMBL394276 | NSC 358285 | Tiazofurin Adenine Din...)
Affinity DataKi:  110nM ΔG°:  -39.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50367389(CHEMBL605602)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50367389(CHEMBL605602)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19253(CHEMBL394276 | NSC 358285 | Tiazofurin Adenine Din...)
Affinity DataKi:  110nM ΔG°:  -39.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19256(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 26...)
Affinity DataKi:  143nM ΔG°:  -39.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19258(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 28...)
Affinity DataKi:  153nM ΔG°:  -38.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19259(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 29...)
Affinity DataKi:  169nM ΔG°:  -38.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19265(C2-Mycophenolic Adenine Dinucleotide (C2-MDA) | CH...)
Affinity DataKi:  250nM ΔG°:  -37.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19260(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 30...)
Affinity DataKi:  255nM ΔG°:  -37.6kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50370187(CHEMBL608195)
Affinity DataKi:  290nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50369298(CHEMBL605601)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50369298(CHEMBL605601)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19265(C2-Mycophenolic Adenine Dinucleotide (C2-MDA) | CH...)
Affinity DataKi:  330nM ΔG°:  -37.0kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50370187(CHEMBL608195)
Affinity DataKi:  330nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50108912(CHEMBL162782 | {Hydroxy-[2-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50108910(CHEMBL348359 | {Hydroxy-[2-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50370188(CHEMBL608194)
Affinity DataKi:  660nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50108912(CHEMBL162782 | {Hydroxy-[2-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  890nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50370188(CHEMBL608194)
Affinity DataKi:  950nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50108910(CHEMBL348359 | {Hydroxy-[2-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD kinase(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50203628(Benzamide adenine dinucleotide | CHEMBL233434 | be...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human NAD kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed