TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Yoshitomi Pharmaceutical Industries
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation at Tyr705 residue in human MCF7 cells preincubated for 1 hr followed by IL-6 stimulation and measure...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation at Tyr705 residue in human MCF7 cells preincubated for 1 hr followed by IL-6 stimulation and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation at Tyr705 residue in human MCF7 cells preincubated for 1 hr followed by IL-6 stimulation and measure...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation at Tyr705 residue in human MCF7 cells preincubated for 1 hr followed by IL-6 stimulation and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of protein farnesyltransferase from human EC17 cells using [3H]FPP and GTP-H-RasMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 5.53E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.45E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair