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Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50030642   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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340n/an/an/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP using CDP-star as substrate by non-competitive Lineweaver-Burk plot


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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590n/an/an/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP using DEA as substrate by non-competitive Lineweaver-Burk plot


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299534
PNG
(5-Bromo-2-methoxy-N-(quinolin-3-yl)benzenesulfonam...)
Show SMILES COc1ccc(Br)cc1S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C16H13BrN2O3S/c1-22-15-7-6-12(17)9-16(15)23(20,21)19-13-8-11-4-2-3-5-14(11)18-10-13/h2-10,19H,1H3
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n/an/a 120n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a 190n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a 230n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP right after mixing with enzyme (EI 0:0) by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a 240n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP after 1 hr incubation with enzyme post-dilution (EI 1:0) by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a 270n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP after 1 hr pre-incubation with enzyme (EI 1:1) by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299525
PNG
(5-chloro-2-methoxy-4-methyl-N-(pyridin-3-yl)benzen...)
Show SMILES COc1cc(C)c(Cl)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H13ClN2O3S/c1-9-6-12(19-2)13(7-11(9)14)20(17,18)16-10-4-3-5-15-8-10/h3-8,16H,1-2H3
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n/an/a 510n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299526
PNG
(5-chloro-2-ethoxy-N-(pyridin-3-yl)benzenesulfonami...)
Show SMILES CCOc1ccc(Cl)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H13ClN2O3S/c1-2-19-12-6-5-10(14)8-13(12)20(17,18)16-11-4-3-7-15-9-11/h3-9,16H,2H2,1H3
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n/an/a 540n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299535
PNG
(2-Methoxy-5-methyl-N-(quinolin-3-yl)benzenesulfona...)
Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O3S/c1-12-7-8-16(22-2)17(9-12)23(20,21)19-14-10-13-5-3-4-6-15(13)18-11-14/h3-11,19H,1-2H3
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n/an/a 650n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299527
PNG
(5-chloro-2-ethoxy-4-methyl-N-(pyridin-3-yl)benzene...)
Show SMILES CCOc1cc(C)c(Cl)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C14H15ClN2O3S/c1-3-20-13-7-10(2)12(15)8-14(13)21(18,19)17-11-5-4-6-16-9-11/h4-9,17H,3H2,1-2H3
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n/an/a 690n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299536
PNG
(2-Methoxy-4-nitro-N-(quinolin-3-yl)benzenesulfonam...)
Show SMILES COc1cc(ccc1S(=O)(=O)Nc1cnc2ccccc2c1)[N+]([O-])=O
Show InChI InChI=1S/C16H13N3O5S/c1-24-15-9-13(19(20)21)6-7-16(15)25(22,23)18-12-8-11-4-2-3-5-14(11)17-10-12/h2-10,18H,1H3
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n/an/a 740n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299524
PNG
(2,5-Dimethoxy-N-(pyridin-3-yl)benzenesulfonamide |...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H14N2O4S/c1-18-11-5-6-12(19-2)13(8-11)20(16,17)15-10-4-3-7-14-9-10/h3-9,15H,1-2H3
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n/an/a 1.06E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299529
PNG
(4-chloro-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulf...)
Show SMILES COc1cc(c(OC)cc1Cl)S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H13ClN2O4S/c1-19-11-7-13(12(20-2)6-10(11)14)21(17,18)16-9-4-3-5-15-8-9/h3-8,16H,1-2H3
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n/an/a 1.13E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299528
PNG
(2-ethoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonami...)
Show SMILES CCOc1ccc(C)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C14H16N2O3S/c1-3-19-13-7-6-11(2)9-14(13)20(17,18)16-12-5-4-8-15-10-12/h4-10,16H,3H2,1-2H3
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n/an/a 1.13E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299530
PNG
(5-fluoro-2-methoxy-N-(pyridin-3-yl)benzenesulfonam...)
Show SMILES COc1ccc(F)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C12H11FN2O3S/c1-18-11-5-4-9(13)7-12(11)19(16,17)15-10-3-2-6-14-8-10/h2-8,15H,1H3
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n/an/a 1.29E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299531
PNG
(2,5-dimethoxy-4-methyl-N-(pyridin-3-yl)benzenesulf...)
Show SMILES COc1cc(c(OC)cc1C)S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C14H16N2O4S/c1-10-7-13(20-3)14(8-12(10)19-2)21(17,18)16-11-5-4-6-15-9-11/h4-9,16H,1-3H3
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n/an/a 1.49E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299532
PNG
(4-bromo-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulfo...)
Show SMILES COc1cc(c(OC)cc1Br)S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H13BrN2O4S/c1-19-11-7-13(12(20-2)6-10(11)14)21(17,18)16-9-4-3-5-15-8-9/h3-8,16H,1-2H3
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n/an/a 1.55E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299533
PNG
(2-methoxy-4,5-dimethyl-N-(pyridin-3-yl)benzenesulf...)
Show SMILES COc1cc(C)c(C)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C14H16N2O3S/c1-10-7-13(19-3)14(8-11(10)2)20(17,18)16-12-5-4-6-15-9-12/h4-9,16H,1-3H3
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n/an/a 1.68E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299537
PNG
(2-Methoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonam...)
Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1cccnc1
Show InChI InChI=1S/C13H14N2O3S/c1-10-5-6-12(18-2)13(8-10)19(16,17)15-11-4-3-7-14-9-11/h3-9,15H,1-2H3
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n/an/a 1.85E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299538
PNG
(2-Methoxy-4-nitro-N-(pyridin-3-yl)benzenesulfonami...)
Show SMILES COc1cc(ccc1S(=O)(=O)Nc1cccnc1)[N+]([O-])=O
Show InChI InChI=1S/C12H11N3O5S/c1-20-11-7-10(15(16)17)4-5-12(11)21(18,19)14-9-3-2-6-13-8-9/h2-8,14H,1H3
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n/an/a 3.16E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299540
PNG
(CHEMBL569638 | N-(2,5-dimethoxybenzyl)quinolin-3-a...)
Show SMILES COc1ccc(OC)c(CNc2cnc3ccccc3c2)c1
Show InChI InChI=1S/C18H18N2O2/c1-21-16-7-8-18(22-2)14(10-16)11-19-15-9-13-5-3-4-6-17(13)20-12-15/h3-10,12,19H,11H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299543
PNG
(5-Chloro-2-methoxy-N-(quinolin-3-yl)benzenesulfona...)
Show SMILES COc1ccc(F)cc1S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C16H13FN2O3S/c1-22-15-7-6-12(17)9-16(15)23(20,21)19-13-8-11-4-2-3-5-14(11)18-10-13/h2-10,19H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299544
PNG
(2,5-Dimethoxy-N-(quinolin-6-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1ccc2ncccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-6-8-16(23-2)17(11-14)24(20,21)19-13-5-7-15-12(10-13)4-3-9-18-15/h3-11,19H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299539
PNG
(2,5-Dimethoxy-N-(naphthalen-2-yl)benzenesulfonamid...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C18H17NO4S/c1-22-16-9-10-17(23-2)18(12-16)24(20,21)19-15-8-7-13-5-3-4-6-14(13)11-15/h3-12,19H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299541
PNG
(CHEMBL572541 | N-(2,5-Dimethoxyphenyl)quinoline-3-...)
Show SMILES COc1ccc(OC)c(NS(=O)(=O)c2cnc3ccccc3c2)c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-13-7-8-17(23-2)16(10-13)19-24(20,21)14-9-12-5-3-4-6-15(12)18-11-14/h3-11,19H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM50299542
PNG
(3-Methoxy-N-(quinolin-3-yl)benzenesulfonamide | CH...)
Show SMILES COc1cccc(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C16H14N2O3S/c1-21-14-6-4-7-15(10-14)22(19,20)18-13-9-12-5-2-3-8-16(12)17-11-13/h2-11,18H,1H3
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PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of IAP by luminescent assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair
Phospholipase A-2-activating protein


(Homo sapiens)
BDBM50299523
PNG
(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C17H16N2O4S/c1-22-14-7-8-16(23-2)17(10-14)24(20,21)19-13-9-12-5-3-4-6-15(12)18-11-13/h3-11,19H,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of PLAP by luminescent assay


J Med Chem 52: 6919-25 (2009)


Article DOI: 10.1021/jm900383s
BindingDB Entry DOI: 10.7270/Q2WS8T9M
More data for this
Ligand-Target Pair