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Found 3 of ic50 for monomerid = 50081173
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50081173(CHEMBL3421972)
Affinity DataIC50:  20nMAssay Description:Inhibition of human wild-type TTK (514 to 795) expressed in insect sf9 cellsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50081173(CHEMBL3421972)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50081173(CHEMBL3421972)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence substrate after 80 mins by caliper off-chip incubation mobility shif...More data for this Ligand-Target Pair