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Found 5 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM36354'
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human ALK2 in presence of (33P)gamma ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  108nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  108nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50:  108nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed