Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM36354'
TargetActivin receptor type-1(Mouse)
Massachusetts Institute of Technology

LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ALK2 in presence of (33P)gamma ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 108nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 108nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetActivin receptor type-1(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 108nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed