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Found 2 Enz. Inhib. hit(s) with Target = 'Epithelial discoidin domain-containing receptor 1' and Ligand = 'BDBM50297825'
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50297825(5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of FLAG-tagged DDR1 in human HEK293 cells assessed as reduction in collagen-1-induced DDR1 phosphorylation incubated for 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50297825(5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human GST-tagged DDR1 expressed in baculovirus expression system incubated for 60 mins by TR-F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed