BDBM50297825 5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)phenylamino)nicotinamide::5-[(2-Methyl-5-{[3- (trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide (1)::5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide::CHEMBL552425
SMILES Cc1ccc(cc1Nc1cncc(c1)C(N)=O)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=SAAYRHKJHDIDPH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50297825
Affinity DataIC50: 19nMAssay Description:The enzymatic activities DDR2 were tested in LanthaScreen binding assays. The protocol is available from Life Technologies.More data for this Ligand-Target Pair
Affinity DataIC50: 753nMAssay Description:The enzymatic activities DDR2 were tested in LanthaScreen binding assays. The protocol is available from Life Technologies.More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of FLAG-tagged DDR1 in human HEK293 cells assessed as reduction in collagen-1-induced DDR1 phosphorylation incubated for 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human GST-tagged DDR2 (427-855 residues) expressed in baculovirus expression system incubated ...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human GST-tagged DDR1 expressed in baculovirus expression system incubated for 60 mins by TR-F...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of ephrinB1-induced autophosphorylation of EphB2 expressed in human U87 cells after 1 hr by western blot analysisMore data for this Ligand-Target Pair