Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-17A' and Ligand = 'BDBM419148'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-17A (Homo sapiens (Human))	BDBM419148 (N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...) Show SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(cc1)S(=O)CC1CCOCC1 Show InChI InChI=1S/C24H33NO4S2/c1-4-20-5-7-22(8-6-20)25(17-19(2)3)31(27,28)24-11-9-23(10-12-24)30(26)18-21-13-15-29-16-14-21/h5-12,19,21H,4,13-18H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...				US Patent US10457637 (2019) BindingDB Entry DOI: 10.7270/Q2WS8WMG
					More data for this Ligand-Target Pair
Interleukin-17A (Homo sapiens (Human))	BDBM419148 (N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...) Show SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(cc1)S(=O)CC1CCOCC1 Show InChI InChI=1S/C24H33NO4S2/c1-4-20-5-7-22(8-6-20)25(17-19(2)3)31(27,28)24-11-9-23(10-12-24)30(26)18-21-13-15-29-16-14-21/h5-12,19,21H,4,13-18H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...				US Patent US10457637 (2019) BindingDB Entry DOI: 10.7270/Q2WS8WMG
					More data for this Ligand-Target Pair