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Found 5 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-2' and Ligand = 'BDBM50099963'
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  16nMAssay Description:Inhibition of ErbB-2 intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  70nMAssay Description:Inhibition of erbB2 overexpressing BT 474 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  97nMAssay Description:Inhibition of erbB2 overexpressing HB4a.e5.2 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Rattus norvegicus)
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  390nMAssay Description:Inhibition of erbB2 overexpressing Calu3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Rattus norvegicus)
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  390nMAssay Description:Inhibition of erbB2 overexpressing Calu3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed