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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50058715'
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  140nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  380nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed