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Found 6 Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM50205308'
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]AVP from vasopressin V2 receptor in rat kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Medical College Of Ohio

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataKi:  23.3nMAssay Description:Binding affinity against human vasopressin V2 receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Medical College Of Ohio

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Medical College Of Ohio

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity of compounds on the human V2 receptor (h V2R) was determined in a transcriptional reporter gene assay by transiently transfecting an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at recombinant rat V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Medical College Of Ohio

Curated by ChEMBL
LigandPNGBDBM50205308((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human vasopressin V2 expressed in HEK293 cells after 5 hrs by firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed