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Found 8 Enz. Inhib. hit(s) with Target = 'Xanthine dehydrogenase/oxidase' and Ligand = 'BDBM50016784'
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataKi:  1.00E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase using xanthine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Universidade Estadual De Campinas

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataKi:  1.55E+3nMAssay Description:Non-competitive inhibition of xanthine oxidase (unknown origin) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataKi:  2.60E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase using hypoxanthine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Universidade Estadual De Campinas

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Universidade Estadual De Campinas

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataIC50:  2.13E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Universidade Estadual De Campinas

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Universidade Estadual De Campinas

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataIC50:  3.50E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate pretreated for 5 mins followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed