Found 113 of ic50 for monomerid = 23926 
Affinity DataKi: 2.15E+4nM IC50: 2.64E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of DPP4 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 4 secs followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
3D Structure (crystal)TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate addition inc...More data for this Ligand-Target Pair
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant COX2 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences
Curated by ChEMBL
Hyogo University Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced current response by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human NQO2 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 913nMAssay Description:Inhibition of human recombinant NQO2 using DCPIPas substrate and NRH as cofactor measured for 1 min by spectrophotometry in the absence of BSAMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 913nMAssay Description:Inhibition of recombinant human NQO2 assessed as change in rate of decolouration of DCPIP measured over 1 min by spectrophotometric methodMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 960nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 960nMpH: 8.0 T: 2°CAssay Description:The activity of recombinant human QR2 under steady-state conditions was evaluated on a MolecularDevices SpectraMax Plus 384 UV-visible spectrophotome...More data for this Ligand-Target Pair
Affinity DataIC50: 996nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
Affinity DataIC50: 996nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant NQO2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in absence of AITCMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant NQO2 using DCPIPas substrate and NRH as cofactor measured for 1 min by spectrophotometry in the prsence of BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human tyrosinase expressed in HEK293 cells using L-tyrosine and DOPA as substrate by absorbance methodMore data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.24E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of self-induced amyloid beta 40 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in presence of AITCMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human DNA polymerase-alpha (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of self-induced amyloid beta 42 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A-23187-stimulated TxB2 productionMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of human recombinant MAO-A by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Campania "L. Vanvitelli
Curated by ChEMBL
University Of Campania "L. Vanvitelli
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of 5-LOX in human PMNL cells assessed as A23187-stimulated LTB4 production preincubated for 15 mins followed by A23187 addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine chloride as substrate pretreated for 15 mins followed by substrate addition measured for...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human serum BuChE using butylthiocholine chloride as substrate pretreated for 15 mins followed by substrate addition measured for 2 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus assessed as reduction in PGE2 synthesis using [3H]arachidonic acid substrate by HPLC an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human MAO-B preincubated for 15 mins followed by p-tyramine substrate addition and measured after 20 mins by Amplex red reagent based f...More data for this Ligand-Target Pair
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of sheep seminal vesicles COX1 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
The University Of Manchester And Manchester Cancer Research Center
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) using N-methyldihydronicotinamide as co-substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human tyrosinase expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University
Curated by ChEMBL
Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human CYP1A1 using ethoxyresorufin as substrate by MROD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of HFIP-pretreated amyloid beta (1 to 42) (unknown origin) self-induced aggregation incubated for 24 hrs under dark condition by thioflavi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of HFIP-pretreated amyloid beta (1 to 42) (unknown origin) self-induced aggregation after 24 hrs by thioflavin-T fluorescence assayMore data for this Ligand-Target Pair
