Found 13 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM23926' TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataIC50: 380nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
Affinity DataIC50: 535nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate addition inc...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A-23187-stimulated TxB2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of sheep seminal vesicles COX1 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S and The Royal London School of Medicine and Dentistry
Curated by PDSP Ki Database
Affinity DataIC50: 1.96E+5nMAssay Description:Inhibition of thrombin-induced platelet aggregation in humanMore data for this Ligand-Target Pair
Affinity DataKd: 1.17E+4nMAssay Description:Binding affinity to COX1 in sheep seminal vesicleMore data for this Ligand-Target Pair
