Compile Data Set for Download or QSAR
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Found 70 of ic50 for UniProtKB: P20839
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112565(CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)
Affinity DataIC50:  46nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)
Affinity DataIC50:  83nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054017((E)-6-(4,6-Dihydroxy-7-methyl-3-oxo-1,3-dihydro-is...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50126005(2-Benzo[b]thiophen-3-yl-6-methoxy-5-oxazol-5-yl-1H...)
Affinity DataIC50:  160nMAssay Description:Inhibition of 5'-inosine monophosphate dehydrogenase type I (IMPDH I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112568(CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220617(CHEMBL47928)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50228085(CHEMBL238461 | N-hydroxy-6-(4-hydroxy-6-methoxy-7-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220681(CHEMBL45658)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220682(CHEMBL46358)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220679(CHEMBL45504)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331099(7-Hydroxy-6-((E)-6-hydroxy-3-methyl-hex-2-enyl)-5-...)
Affinity DataIC50:  770nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220673(CHEMBL48668)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010605(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  940nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50119012(1H-Indole-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010602(3-[2-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010604(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220616(CHEMBL47830)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220671(CHEMBL44696)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331100(CHEMBL237760 | methyl 6-(4-hydroxy-6-methoxy-7-met...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010611(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010609(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220672(CHEMBL416079)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010612(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010606(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010610(3-[2,2-Difluoro-3-(4-hydroxy-6-methoxy-7-methyl-3-...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010603(3-[2,2-Dibromo-3-(4-hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331098(6-(4-acetoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220615(CHEMBL47067)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220618(CHEMBL45771)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010608(3-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.09E+4nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112570(CHEMBL279957 | N-tert-Butyl-N'-[4-(4-methyl-oxazol...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220683(CHEMBL432699)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220620(CHEMBL297980)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50220675(CHEMBL47362)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50127715(3-Methoxy-4-oxazol-5-yl-phenylamine | 3-methoxy-4-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112571(CHEMBL27985 | N-tert-Butyl-N'-(4-oxazol-5-yl-pheny...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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