Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50032473
TargetBcl-2-like protein 1(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM21400(CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(p...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  8nMAssay Description:Binding affinity to BCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  30nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKi:  36nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM21400(CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(p...)
Affinity DataKi:  62nMAssay Description:Binding affinity to BCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKi:  180nMAssay Description:Binding affinity to MCL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKi:  320nMAssay Description:Binding affinity to BCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKi:  480nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCathepsin G(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50329819((R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)b...)
Affinity DataIC50:  13.7nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of CDK6More data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  591nMAssay Description:Agonist activity at RARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  235nMAssay Description:Agonist activity at RARbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCathepsin G(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50329819((R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)b...)
Affinity DataEC50:  13.5nMAssay Description:Inhibition of cathepsin G in human MOLT4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to RETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed