Found 586 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' 
Ligand Info
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41nMAssay Description:Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand Info
Ligand Info
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMpH: 6.5 T: 2°CAssay Description:A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 6.5 T: 2°CAssay Description:A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 9.20nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMpH: 6.5 T: 2°CAssay Description:A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 13nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 15.5nMpH: 6.5 T: 2°CAssay Description:A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...More data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 19.7nMpH: 6.5 T: 2°CAssay Description:A mixture containing 100 mM MES-sodium hydroxide (pH 6.5), 1 mM magnesium acetate, 0.5 mM EGTA, 5 mM beta-mercaptoethanol, 0.02% Tween 20, 10% glycer...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
