TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 2.10nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 120nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 160nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 177nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 210nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 213nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 230nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 234nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 252nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 260nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 624nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 2.80E+3nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 3.75E+3nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 3.90E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.04E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.29E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.41E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.51E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 2.26E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.22E+4nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 4.03E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 5.63E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.18E+5nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University Of The Holy Spirit
US Patent
Duquesne University Of The Holy Spirit
US Patent
Affinity DataIC50: 1.60E+5nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair