Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 2I6B
TargetAdenosine kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14488(5-[4-(dimethylamino)phenyl]-6-{2-[6-(morpholin-4-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14488(5-[4-(dimethylamino)phenyl]-6-{2-[6-(morpholin-4-y...)
Affinity DataIC50:  68nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
TargetAdenosine kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14488(5-[4-(dimethylamino)phenyl]-6-{2-[6-(morpholin-4-y...)
Affinity DataIC50:  68nMAssay Description:Inhibition of adenosine kinase in intact cells assessed as adenosine phosphorylationMore data for this Ligand-Target Pair