Compile Data Set for Download or QSAR
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Found 33 Enz. Inhib. hit(s) with all data for entry = 50008744
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076765((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076764((2-Bromo-4-methylsulfanyl-phenyl)-ethyl-[4-methyl-...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076754((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076746(1-(3-Bromo-4-{ethyl-[4-methyl-6-(2-trifluoromethyl...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076747(2-{2-[(2-Bromo-4-isopropyl-phenyl)-ethyl-amino]-6-...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076768((2,4-Dibromo-phenyl)-ethyl-[4-methyl-6-(2-trifluor...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076766((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-nap...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076756((4-Biphenyl-2-yl-6-methyl-pyrimidin-2-yl)-(2-bromo...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076761((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-[4-methyl-6-(...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074366(CHEMBL10203 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N*...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076751((2-Bromo-4,6-dimethoxy-phenyl)-[4-(2-chloro-phenyl...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076758(2-Bromo-N*1*-ethyl-6-methoxy-N*4*,N*4*-dimethyl-N*...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076775((2-Bromo-4-isopropyl-phenyl)-[4-(2,6-dichloro-phen...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076753((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2,...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076762((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-p...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076759((2-Bromo-4-isopropyl-phenyl)-[4-(2-chloro-phenyl)-...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076772((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(3-...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076757((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-o-t...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076771((2-Bromo-4-methanesulfonyl-phenyl)-ethyl-[4-methyl...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076763((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-(2-fluoro-ph...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076776((2-Bromo-4-isopropyl-phenyl)-[4-(2-bromo-phenyl)-6...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076773((2-Bromo-4-isopropyl-6-methyl-phenyl)-ethyl-[4-met...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076749((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-[4-(2-methoxy...)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076752((2-Bromo-4-isopropyl-phenyl)-[4-(2-dimethylamino-p...)
Affinity DataKi:  78nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076760((4-Biphenyl-3-yl-6-methyl-pyrimidin-2-yl)-(2-bromo...)
Affinity DataKi:  85nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076774((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-phe...)
Affinity DataKi:  109nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076750((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-p...)
Affinity DataKi:  222nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076748((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-p...)
Affinity DataKi:  229nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076767((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...)
Affinity DataKi:  369nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076770((2-Bromo-4-isopropyl-phenyl)-ethyl-{4-methyl-6-[2-...)
Affinity DataKi:  662nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076769(CHEMBL9795 | [4-(2-Amino-phenyl)-6-methyl-pyrimidi...)
Affinity DataKi:  2.36E+3nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076755(2-{2-[(2-Bromo-4-isopropyl-phenyl)-ethyl-amino]-6-...)
Affinity DataKi:  3.54E+3nMAssay Description:Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed