Compile Data Set for Download or QSAR
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Found 74 Enz. Inhib. hit(s) with all data for entry = 50036106
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.350nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.700nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataKi:  1.70nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataKi:  8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataKi:  8nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataKi:  1.50E+3nMAssay Description:Compound was evaluated for the binding affinity by displacing [3H]methylscopolamine [3H]NMS from mouse cerebral cortex tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  23nMAssay Description:The compound was evaluated for the inhibition human of Butyrylcholinesterase IMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005500(CHEMBL13122 | N,N'-Bis-[2-(5-dimethylaminomethyl-f...)
Affinity DataIC50:  25nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005500(CHEMBL13122 | N,N'-Bis-[2-(5-dimethylaminomethyl-f...)
Affinity DataIC50:  28nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  35nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  43nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005504(CHEMBL13206 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  74nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005498(CHEMBL12781 | {5-[4'-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005497(CHEMBL12937 | {5-[4-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005502(CHEMBL12472 | {5-[4-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005493(CHEMBL12858 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005494(CHEMBL418714 | {5-[8-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  310nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005501(CHEMBL275537 | {5-[3-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005492(CHEMBL418712 | {5-[9-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  400nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005496(CHEMBL13426 | {5-[7-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  410nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005492(CHEMBL418712 | {5-[9-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  460nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005493(CHEMBL12858 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  470nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to Muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005494(CHEMBL418714 | {5-[8-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  470nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005500(CHEMBL13122 | N,N'-Bis-[2-(5-dimethylaminomethyl-f...)
Affinity DataIC50:  490nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005503(CHEMBL13308 | {5-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005504(CHEMBL13206 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  500nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005495(CHEMBL13166 | {5-[5-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  520nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to Muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005494(CHEMBL418714 | {5-[8-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  540nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005509(CHEMBL268499 | {5-[6-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  540nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005502(CHEMBL12472 | {5-[4-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  540nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005502(CHEMBL12472 | {5-[4-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  550nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to Muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005492(CHEMBL418712 | {5-[9-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  560nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005509(CHEMBL268499 | {5-[6-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  580nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to Muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005500(CHEMBL13122 | N,N'-Bis-[2-(5-dimethylaminomethyl-f...)
Affinity DataIC50:  590nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005496(CHEMBL13426 | {5-[7-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  610nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005497(CHEMBL12937 | {5-[4-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  630nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005493(CHEMBL12858 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  660nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005498(CHEMBL12781 | {5-[4'-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  680nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005496(CHEMBL13426 | {5-[7-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  710nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005509(CHEMBL268499 | {5-[6-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005495(CHEMBL13166 | {5-[5-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  810nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005504(CHEMBL13206 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  900nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005495(CHEMBL13166 | {5-[5-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human acetylcholinesterase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005492(CHEMBL418712 | {5-[9-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  1.00E+3nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005501(CHEMBL275537 | {5-[3-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005503(CHEMBL13308 | {5-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005504(CHEMBL13206 | N-((5-Ethylsulfanylmethyl-furan-2-yl...)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005498(CHEMBL12781 | {5-[4'-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was evaluated for the inhibition human of Butyrylcholinesterase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50005510(CHEMBL12547 | {5-[10-(5-Dimethylaminomethyl-furan-...)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was evaluated for the inhibition of human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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