Compile Data Set for Download or QSAR
maximum 50k data
Found 71 Enz. Inhib. hit(s) with all data for entry = 50038080
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(CHEMBL15056 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50166984(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50037429(8-(3-chlorostyryl)caffeine | 8-[(E)-2-(3-chlorophe...)
Affinity DataKi:  36nMAssay Description:Antagonist activity against adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50037429(8-(3-chlorostyryl)caffeine | 8-[(E)-2-(3-chlorophe...)
Affinity DataKi:  70nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM9012(7-(6,8-Dichloro-1,2,3,4-tetrahydro-acridin-9-ylami...)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM9022(CHEMBL225567 | Indole-Tacrine Heterodimer 5 | N-[5...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM9023(CHEMBL225198 | Indole-Tacrine Heterodimer 6 | N-[7...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10512(CHEMBL194823 | N-{3-[(6-chloro-1,2,3,4-tetrahydroa...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10692(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50106731((+)-alpha-Lipoic acid | (R)-(+)-lipoic acid | (R)-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50158582(3,8-Diamino-6-phenyl-5-(3-{3-[3-(1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(CHEMBL15056 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50157597(6-[ethyl-(2-methoxy-benzyl)-amino]-1-(1'-{6-[ethyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231957(7-(3-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50166984(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231954(6-[ethyl-(2-methoxy-benzyl)-amino]-hexanoic acid (...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231950(4-((methyl(prop-2-ynyl)amino)methyl)quinolin-8-ol ...)
Affinity DataIC50:  37nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50166984(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human BuchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50:  42nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29400(CHEMBL374184 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10949(3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231950(4-((methyl(prop-2-ynyl)amino)methyl)quinolin-8-ol ...)
Affinity DataIC50:  57nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231956((Z)-8-bromo-4-methyl-3-(methylimino)-1,2,3,4-tetra...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50:  101nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50:  108nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid ...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataIC50:  180nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50041517(4-[(2,6-dichloro-benzyloxyimino)-methyl]-1-(3-phen...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50:  410nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231956((Z)-8-bromo-4-methyl-3-(methylimino)-1,2,3,4-tetra...)
Affinity DataIC50:  540nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231961(3,8-diamino-5-(3-{3-[3-(2-methoxy-benzylamino)-pro...)
Affinity DataIC50:  952nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231957(7-(3-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10826(3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM9022(CHEMBL225567 | Indole-Tacrine Heterodimer 5 | N-[5...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human AchE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231959(4-((prop-2-ynylamino)methyl)quinolin-8-ol | CHEMBL...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10698(3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10826(3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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