Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50027617
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50091116(CHEMBL322983 | N-(2-Phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245929(CHEMBL517867 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218919(CHEMBL242424 | N-(2-m-tolyl-2H-pyrazolo[3,4-c]quin...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218917(CHEMBL242632 | N-(2-p-tolyl-2H-pyrazolo[3,4-c]quin...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254612(CHEMBL454780 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218927(CHEMBL389318 | N-benzoyl-N-(2-phenyl-2H-pyrazolo[3...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254695(3-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245931(5-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254611(CHEMBL519614 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  10.5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254734(4-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254650(CHEMBL464040 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254610(CHEMBL520122 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  15.5nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254651(CHEMBL516851 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataKi:  24.7nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245933(CHEMBL517868 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245930(CHEMBL461151 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  50nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245932(CHEMBL462204 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  50nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254652(CHEMBL464041 | N-(2-(3-(trifluoromethyl)phenyl)-2H...)
Affinity DataKi:  52nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218919(CHEMBL242424 | N-(2-m-tolyl-2H-pyrazolo[3,4-c]quin...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254693(CHEMBL518572 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254609(CHEMBL482183 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254649(CHEMBL463873 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  65nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254692(CHEMBL465096 | N-(2-(4-(trifluoromethyl)phenyl)-2H...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254648(CHEMBL463863 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254694(CHEMBL465945 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  415nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254735(2-(4-(trifluoromethyl)phenyl)-2H-pyrazolo[3,4-c]qu...)
Affinity DataKi:  480nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245931(5-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218917(CHEMBL242632 | N-(2-p-tolyl-2H-pyrazolo[3,4-c]quin...)
Affinity DataKi:  629nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254613(CHEMBL481395 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataKi:  945nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50218919(CHEMBL242424 | N-(2-m-tolyl-2H-pyrazolo[3,4-c]quin...)
Affinity DataKi:  2.68E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245929(CHEMBL517867 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254695(3-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254612(CHEMBL454780 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50245931(5-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254734(4-methyl-N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254611(CHEMBL519614 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataIC50:  76nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254650(CHEMBL464040 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataIC50:  83nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254610(CHEMBL520122 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Affinity DataIC50:  107nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254651(CHEMBL516851 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed