Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50030296
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293841(3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293840(CHEMBL562095 | N-(4-methoxy-3-(piperidin-1-ylsulfo...)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293842(1-(4-morpholinophenylamino)-1-oxopropan-2-yl 1-hyd...)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293843(1,8-diamino-6-methoxy-3-(4-(2-methoxyphenyl)pipera...)
Affinity DataIC50:  4.61E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293839(2-(4-fluoro-3-nitrophenylamino)-N-(4-morpholinophe...)
Affinity DataIC50:  5.72E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed