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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM50293842
Substrate
n/a
Meas. Tech.
ChEMBL_572380 (CHEMBL1035281)
IC50
28300±n/a nM
Citation
 Ferri, N; Corsini, A; Bottino, P; Clerici, F; Contini, A Virtual screening approach for the identification of new Rac1 inhibitors. J Med Chem 52:4087-90 (2009) [PubMed]  Article 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1 | RAC1_HUMAN | Ras-related C3 botulinum toxin substrate 1 | Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 | TC25
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337921
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM50293842
Synonyms:
1-(4-morpholinophenylamino)-1-oxopropan-2-yl 1-hydroxy-2-naphthoate | CHEMBL554475
Type:
Small organic molecule
Emp. Form.:
C24H24N2O5
Mol. Mass.:
420.4578
SMILES:
CC(OC(=O)c1ccc2ccccc2c1O)C(=O)Nc1ccc(cc1)N1CCOCC1
Structure:
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