Compile Data Set for Download or QSAR
maximum 50k data
Found 65 Enz. Inhib. hit(s) with all data for entry = 50030554
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297965((R)-3-(1-(2-chloro-4-(hydroxymethyl)phenyl)ethoxy)...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297962((R)-3-(1-(2-chlorophenyl)ethoxy)-5-(imidazo[1,2-a]...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297966((R)-3-(1-(2-chlorophenyl)ethoxy)-5-(6-(hydroxymeth...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297985((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297971((R)-3-(1-(2-chloro-4-((cyclopropylamino)methyl)phe...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297981((R)-3-(1-(2-chloro-4-((3-oxopiperazin-1-yl)methyl)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297977((R)-3-(1-(2-chloro-4-((4-fluoropiperidin-1-yl)meth...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297982(3-{(R)-1-[2-Chloro-4-(1,1-dioxo-1lambda*6*-thiomor...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297967((R)-3-(1-(2-chloro-4-((methylamino)methyl)phenyl)e...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297978((R)-3-(1-(2-chloro-4-((4-methylpiperazin-1-yl)meth...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297975((R)-3-(1-(2-chloro-4-((3-hydroxypropylamino)methyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297980(3-((1R)-1-(2-chloro-4-((3-hydroxypyrrolidin-1-yl)m...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297984((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297985((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PLK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297969((R)-3-(1-(2-chloro-4-((ethylamino)methyl)phenyl)et...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297974((R)-3-(1-(2-chloro-4-((2-hydroxyethylamino)methyl)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297973((R)-3-(1-(4-((tert-butylamino)methyl)-2-chlorophen...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297968((R)-3-(1-(2-chloro-4-((dimethylamino)methyl)phenyl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297960(5-(imidazo[1,2-a]pyridin-3-yl)-3-(2-(trifluorometh...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297976((R)-3-(1-(2-chloro-4-((1-hydroxy-2-methylpropan-2-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297972((R)-3-(1-(2-chloro-4-((cyclopentylamino)methyl)phe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297979((R)-3-(1-(2-chloro-4-((4-hydroxypiperidin-1-yl)met...)
Affinity DataIC50:  27nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297970((R)-3-(1-(2-chloro-4-((isopropylamino)methyl)pheny...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM28165(5-(1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297961(3-(2-chlorobenzyloxy)-5-(imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297964(3-(1-(2-chloro-5-(hydroxymethyl)phenyl)ethoxy)-5-(...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297983((R)-3-(1-(4-((tert-butylamino)methyl)-2-fluorophen...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297963((R)-3-(1-(2-(hydroxymethyl)phenyl)ethoxy)-5-(imida...)
Affinity DataIC50:  88nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297992(3-(1-(2-chlorophenyl)ethoxy)-5-(7-(hydroxymethyl)i...)
Affinity DataIC50:  92nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297986(5-(pyrazolo[1,5-a]pyridin-3-yl)-3-(2-(trifluoromet...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297993((R)-3-(1-(4-((tert-butylamino)methyl)-2-methylphen...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297985((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataIC50:  178nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297994((R)-3-(1-(4-((tert-butylamino)methyl)-2-cyclopropy...)
Affinity DataIC50:  210nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297991((S)-3-(1-(2-chlorophenyl)ethoxy)-5-(imidazo[1,2-a]...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297987(5-(1-methyl-1H-imidazol-5-yl)-3-(2-(trifluoromethy...)
Affinity DataIC50:  430nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297990(5-(2-benzamidothiazol-5-yl)-3-(2-(trifluoromethyl)...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297988(5-(2-aminothiazol-5-yl)-3-(2-(trifluoromethyl)benz...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297989(5-(2-(phenylamino)thiazol-5-yl)-3-(2-(trifluoromet...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297961(3-(2-chlorobenzyloxy)-5-(imidazo[1,2-a]pyridin-3-y...)
Affinity DataEC50:  1.15E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297960(5-(imidazo[1,2-a]pyridin-3-yl)-3-(2-(trifluorometh...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297963((R)-3-(1-(2-(hydroxymethyl)phenyl)ethoxy)-5-(imida...)
Affinity DataEC50:  3.75E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297964(3-(1-(2-chloro-5-(hydroxymethyl)phenyl)ethoxy)-5-(...)
Affinity DataEC50:  1.16E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297965((R)-3-(1-(2-chloro-4-(hydroxymethyl)phenyl)ethoxy)...)
Affinity DataEC50:  80nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297966((R)-3-(1-(2-chlorophenyl)ethoxy)-5-(6-(hydroxymeth...)
Affinity DataEC50:  210nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297967((R)-3-(1-(2-chloro-4-((methylamino)methyl)phenyl)e...)
Affinity DataEC50:  3.60E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297968((R)-3-(1-(2-chloro-4-((dimethylamino)methyl)phenyl...)
Affinity DataEC50:  4.80E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297969((R)-3-(1-(2-chloro-4-((ethylamino)methyl)phenyl)et...)
Affinity DataEC50:  3.70E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297970((R)-3-(1-(2-chloro-4-((isopropylamino)methyl)pheny...)
Affinity DataEC50:  6.80E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297971((R)-3-(1-(2-chloro-4-((cyclopropylamino)methyl)phe...)
Affinity DataEC50:  2.20E+5nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297972((R)-3-(1-(2-chloro-4-((cyclopentylamino)methyl)phe...)
Affinity DataEC50:  1.21E+5nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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