Compile Data Set for Download or QSAR
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Found 101 Enz. Inhib. hit(s) with all data for entry = 50030386
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295369((2R)-4-(4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295375((2R)-4-(4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295378((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295378((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295379((2R)-1-[(2-Chloro-4-pyrrolidin-1-ylphenyl)sulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295383((2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295383((2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295384((2R)-1-(3-Chloro-4-(2-fluoro-4-(4-fluoro-2-(triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295384((2R)-1-(3-Chloro-4-(2-fluoro-4-(4-fluoro-2-(triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295385((2R)-1-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295385((2R)-1-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295386((2R)-1-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295386((2R)-1-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295387((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295387((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295387((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295388((2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295392((2R)-1-({2-Chloro-4-[(3S)-3-methylpiperazin-1-yl]p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295393((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295393((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295393((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295394((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295394((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295394((2R)-4-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295396((2R)-1-{[2-Chloro-4-(1H-1,2,4-triazol-1-yl)phenyl]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295396((2R)-1-{[2-Chloro-4-(1H-1,2,4-triazol-1-yl)phenyl]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295399((2R)-1-(2-Chloro-4-(difluoromethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295399((2R)-1-(2-Chloro-4-(difluoromethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295401((2R)-1-(2-Chloro-4-(2-methoxyethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295402((2R)-2-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295402((2R)-2-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295403((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295388((2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295368((2R)-1-(4-Bromophenylsulfonyl)-4-(4-fluoro-2-(trif...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295379((2R)-1-[(2-Chloro-4-pyrrolidin-1-ylphenyl)sulfonyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295379((2R)-1-[(2-Chloro-4-pyrrolidin-1-ylphenyl)sulfonyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295400((2R)-1-(2-Chloro-4-ethoxyphenylsulfonyl)-4-(4-fluo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295398((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295397((2R)-1-(4-tert-Butoxy-2-chlorophenylsulfonyl)-4-(4...)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295383((2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295378((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295372((2R)-4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-meth...)
Affinity DataIC50:  16nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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