Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50033622
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50300068(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50348452(AZD-8055 | CHEMBL1801204 | US9102670, 1a)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant mTOR assessed as inhibition of S6K T389 phosphorylation by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mTOR assessed as inhibition of gamma32ATP incorporation to histone H1 by phosphorimagingMore data for this Ligand-Target Pair
LigandPNGBDBM50300068(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50:  677nMAssay Description:Inhibition of p100alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of p100alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed