Found 8 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM36409' TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.More data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR assessed as inhibition of gamma32ATP incorporation to histone H1 by phosphorimagingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using 4EBP1 as substrate in presence of [gamma-32P]ATP by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataIC50: <50nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataKd: 3nMAssay Description:Inhibition of human mTOR (1382 to 2549 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of California San Francisco
University of California San Francisco
Affinity DataKd: 3nMAssay Description:Binding constant for MTOR kinase domainMore data for this Ligand-Target Pair
