Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50032073
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323917(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  10.8nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50:  18.4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50:  62.6nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  76.2nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  83.4nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  84.8nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  92.3nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50:  189nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  226nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50:  237nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  244nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50:  414nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50:  572nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323917(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(CHEMBL1213922 | N-methyl-4-(4-(4-((4-methylpiperaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(CHEMBL1213922 | N-methyl-4-(4-(4-((4-methylpiperaz...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(CHEMBL1213922 | N-methyl-4-(4-(4-((4-methylpiperaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed