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Found 46 Enz. Inhib. hit(s) with all data for entry = 50040519
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395459(CHEMBL2163640)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395459(CHEMBL2163640)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395458(CHEMBL2163637)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395458(CHEMBL2163637)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395456(CHEMBL2163651)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395457(CHEMBL2163636)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50:  17nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395457(CHEMBL2163636)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395454(CHEMBL2163643)
Affinity DataIC50:  18nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395456(CHEMBL2163651)
Affinity DataIC50:  18nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50:  19nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395452(CHEMBL2163642)
Affinity DataIC50:  19nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395451(CHEMBL2163650)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395453(CHEMBL2163644)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395454(CHEMBL2163643)
Affinity DataIC50:  29nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395453(CHEMBL2163644)
Affinity DataIC50:  29nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395450(CHEMBL2163649)
Affinity DataIC50:  33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395452(CHEMBL2163642)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395446(CHEMBL2163646)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395446(CHEMBL2163646)
Affinity DataIC50:  43nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395451(CHEMBL2163650)
Affinity DataIC50:  47nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395450(CHEMBL2163649)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395449(CHEMBL2163648)
Affinity DataIC50:  70nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395448(CHEMBL2163645)
Affinity DataIC50:  88nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395446(CHEMBL2163646)
Affinity DataIC50:  104nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395448(CHEMBL2163645)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395462(CHEMBL2163647)
Affinity DataIC50:  144nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  228nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395462(CHEMBL2163647)
Affinity DataIC50:  304nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395449(CHEMBL2163648)
Affinity DataIC50:  308nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395461(CHEMBL2163652)
Affinity DataIC50:  438nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50: >500nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395461(CHEMBL2163652)
Affinity DataIC50:  851nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395446(CHEMBL2163646)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed