Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50042697
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429614(CHEMBL2334589)
Affinity DataIC50:  20nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429614(CHEMBL2334589)
Affinity DataIC50:  40nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50:  41nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429630(CHEMBL2334970)
Affinity DataIC50:  63nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429634(CHEMBL2334966)
Affinity DataIC50:  63nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429624(CHEMBL2334579)
Affinity DataIC50:  70nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429636(CHEMBL2334964 | US9616064, Compound 15d)
Affinity DataIC50:  76nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429635(CHEMBL2334965)
Affinity DataIC50:  89nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429616(CHEMBL2334583)
Affinity DataIC50:  100nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429626(CHEMBL2334577)
Affinity DataIC50:  110nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429637(CHEMBL2334963)
Affinity DataIC50:  150nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50:  170nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429641(CHEMBL2334591)
Affinity DataIC50:  190nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429638(CHEMBL2334962)
Affinity DataIC50:  300nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429639(CHEMBL2334593)
Affinity DataIC50:  310nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429633(CHEMBL2334967)
Affinity DataIC50:  550nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429613(CHEMBL2334590)
Affinity DataIC50:  600nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429622(CHEMBL2334581)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429632(CHEMBL2334968)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429623(CHEMBL2334580)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429640(CHEMBL2334592)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429616(CHEMBL2334583)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429617(CHEMBL2334588)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429613(CHEMBL2334590)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429621(CHEMBL2334582)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429631(CHEMBL2334969)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429618(CHEMBL2334587)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429620(CHEMBL2334584)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429625(CHEMBL2334578)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429619(CHEMBL2334585)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM10844(4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429629(CHEMBL2334971)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM7641(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429628(CHEMBL2334575)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50429627(CHEMBL2334576)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed