Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50001532
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016343(2-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-m...)
Affinity DataKi:  130nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016340(2-[4-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataKi:  172nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016339(2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl...)
Affinity DataKi:  189nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016342(2-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-meth...)
Affinity DataKi:  205nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016341(2-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-...)
Affinity DataKi:  336nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  35nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50016341(2-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-...)
Affinity DataIC50:  82nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50016342(2-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-meth...)
Affinity DataIC50:  90nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50016343(2-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-m...)
Affinity DataIC50:  310nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50016339(2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl...)
Affinity DataIC50:  540nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50016340(2-[4-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataIC50:  840nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed