Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50045022
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042002(CHEMBL3359576)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042001(CHEMBL3359575)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041996(CHEMBL3359570)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042000(CHEMBL3359574)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041999(CHEMBL3359573)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041993(CHEMBL3359544)
Affinity DataIC50:  61nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041992(CHEMBL3359543)
Affinity DataIC50:  66nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041994(CHEMBL3359545)
Affinity DataIC50:  68nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041995(CHEMBL3359569)
Affinity DataIC50:  68nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358260(CHEMBL1922228)
Affinity DataIC50:  140nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041991(CHEMBL3359542)
Affinity DataIC50:  150nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041997(CHEMBL3359571)
Affinity DataIC50:  220nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041998(CHEMBL3359572)
Affinity DataIC50:  290nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042002(CHEMBL3359576)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Thrombin using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Thrombin using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042002(CHEMBL3359576)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Trypsin using S-2238 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Trypsin using S-2238 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed