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Found 27 Enz. Inhib. hit(s) with all data for entry = 7377
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192120(2-(4-(1-benzoyl-3-(1H-indol-3-yl)-4,5-dihydro-1H-p...)
Affinity DataIC50:  680nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192116((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  740nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192121(2-(4-(1-(4-chlorobenzoyl)-3-(1H-indol-3-yl)-4,5-di...)
Affinity DataIC50:  8.67E+3nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192117((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  9.72E+3nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192114(3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-yl...)
Affinity DataIC50:  1.06E+4nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192122(Ascorbic acid)
Affinity DataIC50:  1.15E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192120(2-(4-(1-benzoyl-3-(1H-indol-3-yl)-4,5-dihydro-1H-p...)
Affinity DataIC50:  1.26E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192122(Ascorbic acid)
Affinity DataIC50:  1.28E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192116((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.31E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192121(2-(4-(1-(4-chlorobenzoyl)-3-(1H-indol-3-yl)-4,5-di...)
Affinity DataIC50:  1.34E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192116((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.35E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192120(2-(4-(1-benzoyl-3-(1H-indol-3-yl)-4,5-dihydro-1H-p...)
Affinity DataIC50:  1.38E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192121(2-(4-(1-(4-chlorobenzoyl)-3-(1H-indol-3-yl)-4,5-di...)
Affinity DataIC50:  1.49E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192117((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.54E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192117((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.55E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192119(2-(4-(1-(2,4-dinitrobenzoyl)-3-(1H-indol-3-yl)-4,5...)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192115((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.61E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192119(2-(4-(1-(2,4-dinitrobenzoyl)-3-(1H-indol-3-yl)-4,5...)
Affinity DataIC50:  1.62E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192115((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  1.74E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192118(2-(4-(3-(1H-indol-3-yl)-1-isonicotinoyl-4,5-dihydr...)
Affinity DataIC50:  2.43E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192114(3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-yl...)
Affinity DataIC50:  2.52E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192118(2-(4-(3-(1H-indol-3-yl)-1-isonicotinoyl-4,5-dihydr...)
Affinity DataIC50:  2.55E+4nMT: 2°CAssay Description:Preparation of DPPH solution was adopted from Molyneux [J. Sci. Technol. 26(2):211-219] and Blois [Nature 181(4617):1199-1200] with minor modificatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192114(3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-yl...)
Affinity DataIC50:  2.55E+4nMT: 2°CAssay Description:The ABTS free radical cation scavenging ability of the synthe- sized compounds was determined according to the procedure described earlier [Free Radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192119(2-(4-(1-(2,4-dinitrobenzoyl)-3-(1H-indol-3-yl)-4,5...)
Affinity DataIC50:  2.71E+4nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192115((3-(1H-indol-3-yl)-5-phenyl-4,5-dihydropyrazol-1-y...)
Affinity DataIC50:  6.08E+4nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aimst University

LigandPNGBDBM192118(2-(4-(3-(1H-indol-3-yl)-1-isonicotinoyl-4,5-dihydr...)
Affinity DataIC50:  8.66E+4nMpH: 8.0 T: 2°CAssay Description:The in vitro AChE inhibitory activity was measured using the methods described earlier [Biochem. Pharmacol. 7:88-95]. Briefly, stock solutions (1mg/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed