Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50007112
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058495(3-{2-[2-(Thiophene-2-carbonylsulfanyl)-propionylam...)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058491(3-{4-[2-(4-{1-[4-(2-Carboxy-2-methyl-propane-1-sul...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058493((R)-2-{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058492((R)-1-{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058474((R)-2-(2-{4-[(6-Hydroxy-3,5,7,8-tetramethyl-chroma...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058480((R)-2-{2-[4-(4-Chloro-benzoylsulfamoyl)-benzoylami...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058486((R)-2-(2-{4-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058475((R)-2-(2-{4-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058485(CHEMBL2373010 | {2-Methyl-1-[(R)-3-(3,3,3-trifluor...)
Affinity DataIC50:  32nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50031201((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50:  34nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058489((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  34nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058481((2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-e...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058487((2R,3aR,7aR)-1-{2-[4-(3,5-Di-tert-butyl-4-hydroxy-...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058471((2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-h...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058477((2R,3aR,7aR)-1-(2-{4-[2-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058478((2R,3aR,7aR)-1-[2-(4-{4-[2-(3,5-Di-tert-butyl-4-hy...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058479(2,6-Dimethyl-4-[4-(4-{2-methyl-1-[(R)-3-(3,3,3-tri...)
Affinity DataIC50:  41nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058483((2R,3aR,7aR)-1-(2-{4-[2-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058490((2R,3aR,7aR)-1-(2-{4-Chloro-3-[2-(3,5-di-tert-buty...)
Affinity DataIC50:  46nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058494(3,5-Di-tert-butyl-4-hydroxy-benzoic acid 2,6-di-te...)
Affinity DataIC50:  46nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058476((S)-1-[(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50:  59nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058482((S)-1-{(R)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058488((S)-1-{(R)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50:  84nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058472((R)-2-(2-Amino-3-methyl-butyryl)-2-aza-bicyclo[2.2...)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  1.00E+3nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against pig pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  2.00E+3nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  1.90E+4nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  2.40E+4nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  3.80E+4nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50:  5.80E+4nMAssay Description:The concentrarion of the compound required to achieve 50% inhibition against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed