Compile Data Set for Download or QSAR
maximum 50k data
Found 61 Enz. Inhib. hit(s) with all data for entry = 50005006
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031406((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  160nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031432((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3...)
Affinity DataEC50:  130nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031386((S)-2-{(S)-2-[(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  1.50E+3nMAssay Description:Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031377(CHEMBL407378 | SFLLRDPQDKYEPF-OH)
Affinity DataEC50:  1.03E+4nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031378((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-pentaf...)
Affinity DataEC50:  6.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031379(Ac-SFLLRDPQDK-NH2 | CHEMBL415138)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031382((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  120nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031381((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  1.00E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031380((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  150nMAssay Description:Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031383((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-cycloh...)
Affinity DataEC50:  2.80E+4nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031385((S)-2-[(S)-3-(4-Aminomethyl-phenyl)-2-((S)-2-amino...)
Affinity DataEC50:  8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031384(CHEMBL406548 | FLLRDPQDK-NH2)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031387((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-4-phenyl...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031388((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-phenyl...)
Affinity DataEC50:  2.60E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031389((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataEC50:  4.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031391((S)-4-Methyl-2-[(S)-2-((S)-2-methylamino-propionyl...)
Affinity DataEC50:  6.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031390((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3...)
Affinity DataEC50:  8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031392((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-h...)
Affinity DataEC50:  200nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031393((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  1.09E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031394((S)-2-{(S)-2-[((S)-2-Amino-3-hydroxy-propionyl)-me...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031395(CHEMBL268064 | SFLLRDPQDK-OH)
Affinity DataEC50:  8.00E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031398((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(3,4-d...)
Affinity DataEC50:  270nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031399((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  1.50E+4nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031396((S)-2-[(S)-2-(4-Amino-butyrylamino)-3-phenyl-propi...)
Affinity DataEC50:  7.30E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031397((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(3,4-d...)
Affinity DataEC50:  500nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031401((S)-2-[(S)-2-(2-Amino-acetylamino)-3-phenyl-propio...)
Affinity DataEC50:  1.20E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031400((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-2-phenyl...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031404((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propion...)
Affinity DataEC50:  1.85E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031403((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  7.00E+4nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031405((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propion...)
Affinity DataEC50:  1.30E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031402((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-met...)
Affinity DataEC50:  2.14E+4nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031409((S)-2-{[(S)-2-((S)-2-Amino-3-hydroxy-propionylamin...)
Affinity DataEC50:  3.50E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031408((S)-2-[(S)-3-(4-Amino-phenyl)-2-((S)-2-amino-propi...)
Affinity DataEC50:  2.35E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031407((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-chl...)
Affinity DataEC50:  700nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031386((S)-2-{(S)-2-[(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  10nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031412((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031410((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-meth...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031411((S)-3-Amino-N-((S)-1-{(S)-1-[(S)-1-((S)-1-carbamoy...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031413((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-flu...)
Affinity DataEC50:  200nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031416((S)-2-Amino-N-((S)-1-carbamoyl-2-phenyl-ethyl)-3-h...)
Affinity DataEC50: >8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031418((S)-2-[(S)-2-((R)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  8.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031414(1-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-...)
Affinity DataEC50:  500nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031417((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-phenyl...)
Affinity DataEC50:  800nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031415((S)-2-[(S)-2-(2-Amino-2-methyl-propionylamino)-3-p...)
Affinity DataEC50:  4.15E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031419((S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataEC50:  2.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031420(CHEMBL263369 | SFLLRDPQDK-NH2)
Affinity DataEC50:  2.00E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031406((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  160nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031421(CHEMBL264249 | SFLLRDPQD-NH2)
Affinity DataEC50:  3.30E+3nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031422((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...)
Affinity DataEC50:  30nMAssay Description:Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031429((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...)
Affinity DataEC50:  5.00E+5nMAssay Description:Evaluated for the activation of human thrombin receptor measured by platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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