Affinity DataIC50: 0.00400nMAssay Description:Inhibition of binding to Growth factor receptor bound protein 2 (Grb2) SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: >5nMAssay Description:Inhibition of interaction between the activated tyrosine kinase receptors and Shp2 SH2 domains in the Ras signal transduction pathway.More data for this Ligand-Target Pair
Affinity DataIC50: >5nMAssay Description:Inhibition of binding to SH2 domain of SHC-PTBMore data for this Ligand-Target Pair
Affinity DataIC50: 6.24nMAssay Description:Inhibition of binding to p56 Lck tyrosine kinase SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 206nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair