Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52466
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52466
Synonyms:
(6E)-2-amino-6-[(4-methoxyanilino)methylidene]-7-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile | (6E)-2-amino-6-[(4-methoxyanilino)methylidene]-7-oxo-4-phenyl-4H-chromene-3-carbonitrile | (6E)-2-amino-7-keto-6-(p-anisidinomethylene)-4-phenyl-4H-chromene-3-carbonitrile | (6E)-2-azanyl-6-[[(4-methoxyphenyl)amino]methylidene]-7-oxidanylidene-4-phenyl-4H-chromene-3-carbonitrile | 2-Amino-7-hydroxy-6-{[(E)-4-methoxy-phenylimino]-methyl}-4-phenyl-4H-chromene-3-carbonitrile | MLS000589519 | SMR000212842 | cid_12005754
Type:
Small organic molecule
Emp. Form.:
C24H19N3O3
Mol. Mass.:
397.426
SMILES:
COc1ccc(cc1)N=Cc1cc2C(C(C#N)C(=N)Oc2cc1O)c1ccccc1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: