Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM50294
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
22568±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM50294
Synonyms:
2-Chloro-5-[3-methyl-5-[1-[5-(2-nitro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-4-oxo-thiazolidin-(2Z)-ylideneamino]-benzoic acid | 2-chloranyl-5-[[(5Z)-3-methyl-5-[[5-(2-nitrophenyl)furan-2-yl]methylidene]-4-oxidanylidene-1,3-thiazolidin-2-ylidene]amino]benzoic acid | 2-chloro-5-[[(5Z)-3-methyl-5-[[5-(2-nitrophenyl)-2-furanyl]methylidene]-4-oxo-2-thiazolidinylidene]amino]benzoic acid | 2-chloro-5-[[(5Z)-3-methyl-5-[[5-(2-nitrophenyl)furan-2-yl]methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acid | 2-chloro-5-[[(5Z)-4-keto-3-methyl-5-[[5-(2-nitrophenyl)-2-furyl]methylene]thiazolidin-2-ylidene]amino]benzoic acid | MLS000590092 | SMR000219301 | cid_1809912
Type:
Small organic molecule
Emp. Form.:
C22H14ClN3O6S
Mol. Mass.:
483.881
SMILES:
CN1\C(S\C(=C/c2ccc(o2)-c2ccccc2[N+]([O-])=O)C1=O)=N/c1ccc(Cl)c(c1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: