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Target
D(1A) dopamine receptor
Ligand
BDBM50035057
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_779
Citation
 Schipper, J; Tulp, MT; Sijbesma, H Neurochemical profile of eltoprazine. Drug Metabol Drug Interact 8:85-114 (1990) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50035057
Synonyms:
(eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | 1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | CHEMBL282614 | Eltoprazine
Type:
Small organic molecule
Emp. Form.:
C12H16N2O2
Mol. Mass.:
220.2676
SMILES:
C1CN(CCN1)c1cccc2OCCOc12
Structure:
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