Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50004603
Substrate
n/a
Meas. Tech.
ChEBML_159622
IC50
>55000±n/a nM
Citation
 Humber, DC; Cammack, N; Coates, JA; Cobley, KN; Orr, DC; Storer, R; Weingarten, GG; Weir, MP Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase. J Med Chem 35:3080-1 (1992) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50004603
Synonyms:
CHEMBL105589 | [4-(2-Acetylamino-ethylcarbamoyl)-5,5-dimethyl-thiazolidin-2-yl]-phenylacetylamino-acetic acid methyl ester
Type:
Small organic molecule
Emp. Form.:
C21H30N4O5S
Mol. Mass.:
450.552
SMILES:
COC(=O)[C@@H](NC(=O)Cc1ccccc1)[C@@H]1N[C@@H](C(=O)NCCNC(C)=O)C(C)(C)S1
Structure:
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