Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50005471
Substrate
n/a
Meas. Tech.
ChEMBL_47648 (CHEMBL657360)
Ki
180±n/a nM
Citation
 van der Bent, A; Blommaert, AG; Melman, CT; IJzerman, AP; van Wijngaarden, I; Soudijn, W Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718. J Med Chem 35:1042-9 (1992) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50005471
Synonyms:
1H-Indole-2-carboxylic acid (3-phenyl-allyl)-amide | CHEMBL9220
Type:
Small organic molecule
Emp. Form.:
C18H16N2O
Mol. Mass.:
276.3324
SMILES:
O=C(NC\C=C\c1ccccc1)c1cc2ccccc2[nH]1
Structure:
Search PDB for entries with ligand similarity: