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Target
Adenosine deaminase
Ligand
BDBM50088426
Substrate
n/a
Meas. Tech.
ChEBML_31100
Ki
9900±n/a nM
Citation
 Vince, R; Brownell, J; Daluge, S Carbocyclic analogues of xylofuranosylpurine nucleosides. Synthesis and antitumor activity. J Med Chem 27:1358-60 (1984) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA_MOUSE | Ada
Type:
PROTEIN
Mol. Mass.:
39984.63
Organism:
Mus musculus
Description:
ChEMBL_31100
Residue:
352
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ
  
Inhibitor
Name:
BDBM50088426
Synonyms:
(1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol | 3-(6-Amino-purin-9-yl)-5-hydroxymethyl-cyclopentane-1,2-diol | CHEMBL49935
Type:
Small organic molecule
Emp. Form.:
C11H15N5O3
Mol. Mass.:
265.2685
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O
Structure:
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